Job Information
Labcorp Staff Software Engineer, Variant Classification in Remote, North Carolina
Labcorp is seeking a Staff Software Engineer, Variant Classification to join our Labcorp Genetics team.
Work Schedule: This is a full‑time, exempt (salaried) position assigned to a First Shift schedule, with standard business hours of Monday through Friday, 8:00 a.m. to 5:00 p.m. in your local time zone. Business needs may occasionally require flexibility in work hours, including earlier, later, or additional hours, with reasonable notice provided when possible.
Applicants who live within 35 miles of either the Burlington, NC or Durham, NC location will follow a hybrid schedule. This schedule includes a minimum of three in-office days per week at an assigned location, either Burlington or Durham, supporting both collaboration and flexibility.
Job Responsibilities:
Design and build tools that define, store, and provide meaningful variant, sample, and test level information to supportaccuratevariant interpretation and report generation
Develop andmaintainsystems that translate raw bioinformatic data into variant and sample level information, including registration, normalization, observation groups, and quality metrics
Scale andoptimizestorage of sample level information to support growing data needs
Source,maintain, and provide annotations at the variant level necessary foraccuratevariant interpretation
Automate evidence placement and classification for variant interpretation
Support test content and assay development initiatives
Collaborate with data scientists, variant scientists, and software developers to design and implement solutions that meet stakeholder requirements
Minimum Qualifications:
Bachelor's degree with 10 or more years of recent professional software development experience
10 or more years of experience with Python (intermediate level or higher)
10 or more years of experience with relational databases and web development frameworks
10 or more years of experience with front-end technologies (e.g., React, Angular, Vue.js, JavaScript/TypeScript, HTML/CSS)
10 or more years of experience with RESTful APIs and microservices architecture
10 or more years of experience with CI/CD pipelines and DevOps practices
10 or more years of experience with cloud platforms (AWS, Azure, or GCP)
Preferred Qualifications:
Master's Degree or Ph.D. in Bioinformatics/Computational Biology or life sciences
8 or more years of experience mentoring and developing senior and junior engineers across multiple teams
8 or more years of experience defining technical vision and driving multi-year roadmaps
3 or more years of experience with bioinformatic tools and annotation
3 or more years of experience with variant databases and genomic data resources (e.g.,ClinVar,gnomAD, HGMD)
3 or more years of experience in Spark, text mining, natural language processing, semantic enrichment, ontologies, data mining, or machine learning/AI
3 or more years of experience with public-domain biomedical terminologies (e.g.,MeSH, NCIt, HGNC)
3 or more years of experience translating complex scientific questions into information solutions
Additional Job Standards:
Owns and delivers product or platform goals across multiple years and teams, setting a high standard for technical outcomes and delivery
Defines the vision, scope, and technical approach for large, business-impacting projects with organization-wide implications
Identifies, prioritizes, and drives solutions to ambiguous, open-ended problems across multiple teams
Influences the roadmaps of partner teams to align with and achieve broader business goals
Serves as a role model and technical authority for engineers across multiple teams
Effective verbal and written communicator with both scientific and non-scientific audiences
Effective with GitHub Copilot, Claude Code or similar LLM tools to accelerate coding, testing and documentation
About Labcorp Genetics
Labcorp Genetics (formerly Invitae) is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. The Variant Classification team builds and maintains the tools that define, store, and provide meaningful and detailed variant, sample, and test level information to support accurate variant interpretation and report generation. Our services support interpretation reporting of genetic variants and assay development across a suite of critical platforms including SDS, VDB, Argus, iVEP, Evidence Service, MoonPy, Cerebro, Universal Transcript Archive, SeqRepo, and Assay CMS.
At Labcorp we have a passion for helping people live happy and healthy lives. Every day we provide vital information that helps our clients and patients understand their health. If you are passionate about helping people and have a drive for service, then Labcorp could be a great next career step!
Application Window: 3/15/2026
Pay Range: $100K - $198K/yr
All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data.
LBP Only: The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.
Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. Employees who are regularly scheduled to work a 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information, please click here (https://careers.labcorp.com/global/en/us-rewards-and-wellness) .
Labcorp is proud to be an Equal Opportunity Employer:
Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.
We encourage all to apply
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