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ATS Automation MES Opcenter Pharma Engineer (m/f/d) in Antwerp, Belgium

ATS Company: PA Solutions

Requisition ID: 16835

Location:

Antwerp, Antwerp, BE, 2600

Date: Apr 2, 2026

MES Opcenter Pharma Engineer (m/f/d)

To support a large-scale Manufacturing Execution System (MES) transformation program at one of our Customers, we are looking for aMedior to Senior MES Opcenter Pharma Engineer (m/f/d).

You will play a key role in the design, configuration, validation, and deployment of SiemensOpcenter Execution Pharma within a GMP-regulated manufacturing environment. You will work closely with process experts, QA, IT, automation, and business stakeholders to translate manufacturing requirements into compliant and robust MES solutions.

Your responsibilities:

MES Design & Implementation

  • Design, configure, and implement Siemens Opcenter Execution Pharma solutions aligned with shop-floor manufacturing processes

  • Translate User Requirements (URS) into functional and technical MES design

  • Configure electronic batch records (EBR), workflows, recipes, material tracking, and equipment modeling

  • Support integration with DCS/PLC systems, ERP (e.g. SAP), and other manufacturing systems

Project & Delivery Support

  • Participate in full MES project lifecycle: analysis, design, build, testing, deployment, and hypercare

  • Contribute to technical discussions with both business and IT stakeholders

  • Support system deployment across different manufacturing areas or sites (as applicable)

Validation & Compliance

  • Ensure MES solutions comply with GMP, GAMP5, and 21 CFR Part 11 requirements

  • Support CSV activities including risk assessments, specifications, test protocols, and deviation handling

  • Align with quality standards, SOPs, and validation frameworks

Testing & Go Live

  • Prepare and execute FAT/SAT, integration testing, and UAT support

  • Support manufacturing during go live and ramp up phases

  • Troubleshoot MES-related issues in collaboration with IT, QA, and operations

Collaboration & Knowledge Sharing

  • Act as a technical reference within the MES team

  • Coach and support more junior MES engineers (senior profiles)

  • Document solutions and contribute to standardization and best practices

Your Profile:

  • Sound experience of multiple years working with MES systems in a pharmaceutical or life sciences environment

  • Proven hands on experience with Siemens Opcenter Execution Pharma

  • Strong understanding of pharma manufacturing processes (batch manufacturing, materials management, equipment modeling)

  • Experience with MES integrations (ERP, automation, serialization is a plus)

  • Solid understanding of GMP, GAMP 5, and CSV principles

  • Familiarity with electronic records, audit trails, and system security concepts

  • Strong analytical and problem-solving skills

  • Able to communicate clearly with both technical and non technical stakeholders

  • Comfortable working in large, structured enterprise programs

  • Proactive mindset and ownership mentality

  • Business Fluency in English, able to communicate clearly with both technical and non technical stakeholders

  • Dutch/Flemish and French business fluency are advantage

Nice to Have / Assets

  • Experience working in large pharma programs

  • Experience with Siemens Opcenter Execution Core / MBR Designer

  • Knowledge of ISA 95 / ISA 88 concepts

  • Experience in multi-site MES rollouts

  • Previous exposure to DCS/PLC environments

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